Donovan's solution

Donovan's Solution
Names
	IUPAC name Iodomercury; triiodoarsane
	Other names Liquor hydriodatis arsenici et hydrargyri
Identifiers
CAS Number	8012-54-2 ;
3D model (JSmol)	Interactive image;
ChemSpider	23077;
PubChem CID	24679;
RTECS number	CG3200000;
UN number	1557
CompTox Dashboard (EPA)	DTXSID00230082 ;
	InChI InChI=1S/AsI3.Hg.HI/c2-1(3)4;;/h;;1H/q;+1;/p-1 Key: QLULWSBMTZWVDE-UHFFFAOYSA-M;
	SMILES [As](I)(I)I.I[Hg];
Properties
Chemical formula	AsHgI4
Molar mass	783.12948
Appearance	Clear, colourless, or pale yellow. Darkens with age.
Boiling point	403 °C (757 °F; 676 K) at 760 mmHg
Solubility in water	Yes
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Toxic
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Donovan's solution is an inorganic compound prepared from arsenic triiodide and mercuric iodide.^[1] Despite its name, it is a compound and not a solution.

Method

Donovan's solution can be prepared by mixing arsenic triiodide, mercuric iodide, and sodium bicarbonate in aqueous solution.^[2]^[3]

Cooley's cyclopædia of practical receipts and ... information on the arts, manufactures, and trades gives a more complex method.^[4]

Uses

The solution been used in veterinary medicine to treat chronic diseases of the skin^[3] and as a folk remedy.^[5] It was used during the 19th century to treat lepra vulgaris^[6] and psoriasis^[7]^[8] in humans, taken internally.

References

^ Budavari, Susan (1989). "3413. Donovan's Solution". The Merck Index (11th ed.). Merck & Co., Inc. p. 537. ISBN 091191028X. LCCN 89060001.
^ Navy Department. Bureau of Medicine and Surgery (1950). Pharmacy and Materia Medica: Military-medical Operations Courses. Bureau of Naval Personnel. p. 17.
^ ^a ^b Oxtoby, David W.; H.P. Gillis; Allan Campion (2012). Principles of modern chemistry (7th ed.). Belmont, Calif.: Brooks/Cole Cengage Learning. p. 513. ISBN 978-0840049315.
^ Arnold James Cooley (1880). "Solution". In Richard Vine Tuson (ed.). A cyclopædia of practical receipts and ... information on the arts, manufactures, and trades. Vol. II (6th ed.). p. 1525.
^ "Donovan's solution". Chemical Dictionary Online. Retrieved 29 November 2013.
^ Sir Erasmus Wilson (1847). "Treatment of Lepra". On Diseases of the Skin (2nd ed.). John Churchill. p. 271.
^ Henry G. Piffard (1881). "Psoriasis Treatment. Part 6". A Treatise On The Materia Medica And Therapeutics Of The Skin. Sampson, Low, Marston, Searle & Rivington. p. 254.
^ "Good Results of Donovan's Solution in Psoriasis". The Lancet. 70 (1770): 116. August 1857. doi:10.1016/S0140-6736(02)38789-0.

[1] Budavari, Susan (1989). "3413. Donovan's Solution". The Merck Index (11th ed.). Merck & Co., Inc. p. 537. ISBN 091191028X. LCCN 89060001.

[2] Navy Department. Bureau of Medicine and Surgery (1950). Pharmacy and Materia Medica: Military-medical Operations Courses. Bureau of Naval Personnel. p. 17.

[:0-3] Oxtoby, David W.; H.P. Gillis; Allan Campion (2012). Principles of modern chemistry (7th ed.). Belmont, Calif.: Brooks/Cole Cengage Learning. p. 513. ISBN 978-0840049315.

[4] Arnold James Cooley (1880). "Solution". In Richard Vine Tuson (ed.). A cyclopædia of practical receipts and ... information on the arts, manufactures, and trades. Vol. II (6th ed.). p. 1525.

[5] "Donovan's solution". Chemical Dictionary Online. Retrieved 29 November 2013.

[6] Sir Erasmus Wilson (1847). "Treatment of Lepra". On Diseases of the Skin (2nd ed.). John Churchill. p. 271.

[7] Henry G. Piffard (1881). "Psoriasis Treatment. Part 6". A Treatise On The Materia Medica And Therapeutics Of The Skin. Sampson, Low, Marston, Searle & Rivington. p. 254.

[8] "Good Results of Donovan's Solution in Psoriasis". The Lancet. 70 (1770): 116. August 1857. doi:10.1016/S0140-6736(02)38789-0.

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