Chorionic bump

Chorionic bump is a rare medical condition defined as an irregular, convex bulge or protrusion from the choriodecidual surface into the gestational sac.[1][2] It is medically defined as a separate entity from a chorionic hematoma.[3]

Identification of a chorionic bump in early first trimester pregnancy represents a significant risk factor for pregnancy loss, given a live birth rate of less than 50%.[4] The incidence rate for chorionic bump is estimated to be between 1.5 to 7 per 1000 pregnancies.[5]

Cause and diagnosis

edit

It is believed that chorionic bump can start as a hematoma in the intervillous space.[6] Additionally, infertility treatments may be associated with increased likelihood of chorionic bump.[7]

Prognosis and treatment

edit

Existing literature suggests that chorionic bump causes first trimester pregnancy loss and doubles the miscarriage rate as compared to having no risk factors.[8]

References

edit
  1. ^ Yousaf, Amman; Tayyab, Ahmad; Anil, Muhammad Sana Ullah; Ahmed, Mohamed Mohamed Helmi; Sr, Sana Sayed Hussein Badr Ahmed Ahmed; Alobadli, Amal; Yousaf, Amman; Tayyab, Ahmad; Anil, Muhammad S.; Ahmed, Mohamed Mohamed Helmi; Sr, Sana Sayed Hussein Badr Ahmed Ahmed; Alobadli, Amal (2020-11-14). "Chorionic Bump: Radiologic Features and Pregnancy Outcomes". Cureus. 12 (11): e11480. doi:10.7759/cureus.11480. ISSN 2168-8184. PMC 7735167. PMID 33329976.
  2. ^ Liu, Emily; Noor, Abdul; Pereira, Nigel (2024-07-01). "Chorionic Bump: An Early Marker for Miscarriage and Embryonic Aneuploidy?". Journal of Obstetrics and Gynaecology Canada. 46 (7). doi:10.1016/j.jogc.2024.102576. ISSN 1701-2163. PMID 38852808.
  3. ^ Sana, Y.; Appiah, A.; Davison, A.; Nicolaides, K. H.; Johns, J.; Ross, J. A. (2013). "Clinical significance of first-trimester chorionic bumps: a matched case–control study". Ultrasound in Obstetrics & Gynecology. 42 (5): 585–589. doi:10.1002/uog.12528. ISSN 1469-0705.
  4. ^ Harris, Robert D.; Couto, Corey; Karpovsky, Clara; Porter, Misty M. Blanchette; Ouhilal, Sophia (2006). "The Chorionic Bump". Journal of Ultrasound in Medicine. 25 (6): 757–763. doi:10.7863/jum.2006.25.6.757. ISSN 1550-9613. PMID 16731892.
  5. ^ Sana, Y.; Appiah, A.; Davison, A.; Nicolaides, K. H.; Johns, J.; Ross, J. A. (2013). "Clinical significance of first-trimester chorionic bumps: a matched case–control study". Ultrasound in Obstetrics & Gynecology. 42 (5): 585–589. doi:10.1002/uog.12528. ISSN 1469-0705.
  6. ^ Younesi, Ladan; Shahnazari, Razieh (2017-12-01). "Chorionic Bump in First-trimester Sonography". Journal of Medical Ultrasound. 25 (4): 221–226. doi:10.1016/j.jmu.2017.04.004. ISSN 0929-6441. PMC 6029338. PMID 30065496.
  7. ^ Harris, Robert D.; Couto, Corey; Karpovsky, Clara; Porter, Misty M. Blanchette; Ouhilal, Sophia (2006). "The Chorionic Bump". Journal of Ultrasound in Medicine. 25 (6): 757–763. doi:10.7863/jum.2006.25.6.757. ISSN 1550-9613. PMID 16731892.
  8. ^ Harris, Robert D.; Couto, Corey; Karpovsky, Clara; Porter, Misty M. Blanchette; Ouhilal, Sophia (2006). "The Chorionic Bump". Journal of Ultrasound in Medicine. 25 (6): 757–763. doi:10.7863/jum.2006.25.6.757. ISSN 1550-9613. PMID 16731892.