Duchess of Grafton is the title given to the wife of the Duke of Grafton. Women who have held the title include:
- Isabella FitzRoy, Duchess of Grafton (1668–1723)
- Anne FitzPatrick, Countess of Upper Ossory (1737–1804), who was duchess from 1757 until her divorce in 1769.
- Fortune FitzRoy, Duchess of Grafton (1920–2021)
This disambiguation page lists articles associated with the title Duchess of Grafton.
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