ECD (gene)

Protein SGT1 is a protein that in humans is encoded by the ECD gene.

ECD
Identifiers
Aliases	ECD, GCR2, HSGT1, SGT1, ecdysoneless cell cycle regulator
External IDs	OMIM: 616464; MGI: 1917851; HomoloGene: 5256; GeneCards: ECD; OMA:ECD - orthologs
Gene location (Human) Chr. Chromosome 10 (human) Band 10q22.2 Start 73,130,155 bp End 73,169,055 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 A3 Start 20,369,920 bp End 20,398,189 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve Achilles tendon islet of Langerhans ganglionic eminence tendon of biceps brachii popliteal artery tibial arteries ventricular zone testicle stromal cell of endometrium Top expressed in internal carotid artery external carotid artery Rostral migratory stream fetal liver hematopoietic progenitor cell spermatocyte epiblast primitive streak hair follicle lacrimal gland parotid gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transcription coactivator activity protein binding histone acetyltransferase binding Cellular component cytoplasm nucleus nucleoplasm R2TP complex cytosol Biological process regulation of G1/S transition of mitotic cell cycle cell population proliferation regulation of transcription, DNA-templated transcription by RNA polymerase II transcription, DNA-templated regulation of glycolytic process positive regulation of transcription by RNA polymerase II RNA splicing mRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11319 70601 Ensembl ENSG00000122882 ENSMUSG00000021810 UniProt O95905 Q9CS74 RefSeq (mRNA) NM_001135752 NM_001135753 NM_007265 NM_027475 RefSeq (protein) NP_001129224 NP_001129225 NP_009196 NP_081751 Location (UCSC) Chr 10: 73.13 – 73.17 Mb Chr 14: 20.37 – 20.4 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Bork JM, Peters LM, Riazuddin S, et al. (2001). "Usher Syndrome 1D and Nonsyndromic Autosomal Recessive Deafness DFNB12 Are Caused by Allelic Mutations of the Novel Cadherin-Like Gene CDH23". Am. J. Hum. Genet. 68 (1): 26–37. doi:10.1086/316954. PMC 1234923. PMID 11090341.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Nowotny M, Spiechowicz M, Jastrzebska B, et al. (2003). "Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins". J. Biol. Chem. 278 (29): 26923–8. doi:10.1074/jbc.M211518200. PMID 12746458.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.