ER degradation-enhancing alpha-mannosidase-like 2 is an enzyme that in humans is encoded by the EDEM2 gene.[5][6][7]

EDEM2
Identifiers
AliasesEDEM2, C20orf31, C20orf49, bA4204.1, ER degradation enhancing alpha-mannosidase like protein 2
External IDsOMIM: 610302; MGI: 1915540; HomoloGene: 10075; GeneCards: EDEM2; OMA:EDEM2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001145025
NM_018217

NM_145537

RefSeq (protein)

NP_001138497
NP_060687

NP_663512

Location (UCSC)Chr 20: 35.12 – 35.15 MbChr 2: 155.54 – 155.57 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000088298Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038312Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Mast SW, Diekman K, Karaveg K, Davis A, Sifers RN, Moremen KW (Mar 2005). "Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins". Glycobiology. 15 (4): 421–36. doi:10.1093/glycob/cwi014. PMID 15537790.
  6. ^ Olivari S, Galli C, Alanen H, Ruddock L, Molinari M (Jan 2005). "A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation". J Biol Chem. 280 (4): 2424–8. doi:10.1074/jbc.C400534200. PMID 15579471.
  7. ^ "Entrez Gene: EDEM2 ER degradation enhancer, mannosidase alpha-like 2".

Further reading

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