El Guapo (Spanish for "The Handsome") or Guapo may refer to:

Arts and entertainment

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  • El Guapo (band), later Supersystem, an American band
  • Guapo (band), a British art rock band
  • El Guapo, a Marvel Comics character in the superhero team X-Statix
  • El Guapo, a fictional character in the 1986 film Three Amigos
  • El Guapo, gaming alias of the young Sylvester Dodd in Scorpion (TV series). First mentioned in season 1, episode 13 - “Kill Screen.”

Nickname or stage name

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  • Rich Garcés (born 1971), American baseball pitcher
  • David Guapo, David Callejón (born 1981), Spanish comedian and singer
  • Bas Rutten (born 1965), Dutch-American actor and MMA fighter

Places

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