Wikipedia

Emma Raven

Emma Raven (née Lloyd, born 1967) is a British chemist and chemical biologist. She is a Professor of Chemistry [1] at the University of Bristol. She was previously a Professor at the University of Leicester. Her research work is concerned with the role of heme in biology,[2][3][4] in particular on the mechanism of action,[5][6] structures and biological function of heme proteins.[7][8][9][10][11][12][13]

FRSC, CChem
Emma Raven
Born
Emma Lloyd

1967
Northamptonshire
NationalityBritish
Alma materUniversity of Leicester (BSc)
Newcastle University (PhD)
Occupation(s)Professor of Chemistry
(University of Bristol)
OrganizationUniversity of Bristol
AwardsFellow of the Royal Society of Chemistry (FRSC)
Inorganic Biochemistry Award (2005)
Reaction Kinetics and Mechanism Award (2008)
Royal Society Wolfson Award (2017)
Interdisciplinary Prize (2020)
Websitehttps://emmaravenresearchgroup.wordpress.com/

Biography

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Emma was born in Northamptonshire and was educated in state schools at Ruskin Junior[14] and then Weavers School.[15] She obtained a first class degree in chemistry from the University of Leicester in 1988. She subsequently moved to Newcastle University when she obtained her PhD in 1991, supervised by A Geoffrey Sykes, FRS.

Career

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With encouragement from A G Sykes, in 1992 she moved to the University of British Columbia where she worked with A G Mauk[16] and Michael Smith, FRS. In 1994, she was offered a lectureship at the University of Leicester, where she worked for 23 years. In 2018, she moved to the University of Bristol.

Awards and honours

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Emma is a Fellow of the Royal Society of Chemistry (FRSC). She has received several awards from the Royal Society of Chemistry, including the Inorganic Biochemistry Award[17] (2005), the Reaction Kinetics and Mechanism Award[18] (2008), and the Interdisplinary Prize (2020). She also received a Royal Society Wolfson Award in 2017. She has been the recipient of research fellowships from the Wellcome Trust (2001), the Leverhulme Trust (2005, 2017) and the BBSRC (2006, 2013). She has served as President of the Royal Society of Chemistry Dalton (Inorganic) Division (2016-2018).[19]

Family

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Emma married Neil Raven in 1998. She has two younger brothers, both of them scientists; one of them, Daniel Lloyd,[20] is a professor at the University of Kent.  

References

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  1. ^ Bristol, University of. "School of Chemistry | School of Chemistry | University of Bristol". www.bris.ac.uk. Retrieved 2020-08-26.
  2. ^ Burton, Mark J.; Kapetanaki, Sofia M.; Chernova, Tatyana; Jamieson, Andrew G.; Dorlet, Pierre; Santolini, Jérôme; Moody, Peter C. E.; Mitcheson, John S.; Davies, Noel W.; Schmid, Ralf; Raven, Emma L. (2016-04-05). "A heme-binding domain controls regulation of ATP-dependent potassium channels". Proceedings of the National Academy of Sciences. 113 (14): 3785–3790. Bibcode:2016PNAS..113.3785B. doi:10.1073/pnas.1600211113. ISSN 0027-8424. PMC 4833257. PMID 27006498.
  3. ^ Kapetanaki, Sofia M.; Burton, Mark J.; Basran, Jaswir; Uragami, Chiasa; Moody, Peter C. E.; Mitcheson, John S.; Schmid, Ralf; Davies, Noel W.; Dorlet, Pierre; Vos, Marten H.; Storey, Nina M. (December 2018). "A mechanism for CO regulation of ion channels". Nature Communications. 9 (1): 907. Bibcode:2018NatCo...9..907K. doi:10.1038/s41467-018-03291-z. ISSN 2041-1723. PMC 5834611. PMID 29500353.
  4. ^ Freeman, Samuel L.; Kwon, Hanna; Portolano, Nicola; Parkin, Gary; Venkatraman Girija, Umakhanth; Basran, Jaswir; Fielding, Alistair J.; Fairall, Louise; Svistunenko, Dimitri A.; Moody, Peter C. E.; Schwabe, John W. R. (2019-10-01). "Heme binding to human CLOCK affects interactions with the E-box". Proceedings of the National Academy of Sciences. 116 (40): 19911–19916. doi:10.1073/pnas.1905216116. ISSN 0027-8424. PMC 6778266. PMID 31527239.
  5. ^ Lad, Latesh; Mewies, Martin; Raven, Emma Lloyd (November 2002). "Substrate Binding and Catalytic Mechanism in Ascorbate Peroxidase: Evidence for Two Ascorbate Binding Sites †". Biochemistry. 41 (46): 13774–13781. doi:10.1021/bi0261591. ISSN 0006-2960. PMID 12427040.
  6. ^ Sharp, Katherine H.; Mewies, Martin; Moody, Peter C.E.; Raven, Emma Lloyd (April 2003). "Crystal structure of the ascorbate peroxidase–ascorbate complex". Nature Structural & Molecular Biology. 10 (4): 303–307. doi:10.1038/nsb913. ISSN 1545-9993. PMID 12640445. S2CID 32035409.
  7. ^ Gumiero, Andrea; Metcalfe, Clive L.; Pearson, Arwen R.; Raven, Emma Lloyd; Moody, Peter C. E. (2011-01-14). "Nature of the Ferryl Heme in Compounds I and II". Journal of Biological Chemistry. 286 (2): 1260–1268. doi:10.1074/jbc.M110.183483. ISSN 0021-9258. PMC 3020733. PMID 21062738.
  8. ^ Casadei, C. M.; Gumiero, A.; Metcalfe, C. L.; Murphy, E. J.; Basran, J.; Concilio, M. G.; Teixeira, S. C. M.; Schrader, T. E.; Fielding, A. J.; Ostermann, A.; Blakeley, M. P. (2014-07-11). "Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase" (PDF). Science. 345 (6193): 193–197. Bibcode:2014Sci...345..193C. doi:10.1126/science.1254398. hdl:2381/29117. ISSN 0036-8075. PMID 25013070. S2CID 20942802.
  9. ^ Moody, Peter C. E.; Raven, Emma L. (2018-02-20). "The Nature and Reactivity of Ferryl Heme in Compounds I and II". Accounts of Chemical Research. 51 (2): 427–435. doi:10.1021/acs.accounts.7b00463. ISSN 0001-4842. PMID 29327921.
  10. ^ Kwon, Hanna; Basran, Jaswir; Devos, Juliette M.; Suardíaz, Reynier; van der Kamp, Marc W.; Mulholland, Adrian J.; Schrader, Tobias E.; Ostermann, Andreas; Blakeley, Matthew P.; Moody, Peter C. E.; Raven, Emma L. (2020-03-24). "Visualizing the protons in a metalloenzyme electron proton transfer pathway". Proceedings of the National Academy of Sciences. 117 (12): 6484–6490. doi:10.1073/pnas.1918936117. ISSN 0027-8424. PMC 7104402. PMID 32152099.
  11. ^ Chauhan, Nishma; Thackray, Sarah J.; Rafice, Sara A.; Eaton, Graham; Lee, Michael; Efimov, Igor; Basran, Jaswir; Jenkins, Paul R.; Mowat, Christopher G; Chapman, Stephen K.; Raven, Emma Lloyd (April 2009). "Reassessment of the Reaction Mechanism in the Heme Dioxygenases". Journal of the American Chemical Society. 131 (12): 4186–4187. doi:10.1021/ja808326g. ISSN 0002-7863. PMID 19275153.
  12. ^ Basran, Jaswir; Efimov, Igor; Chauhan, Nishma; Thackray, Sarah J.; Krupa, James L.; Eaton, Graham; Griffith, Gerry A.; Mowat, Christopher G.; Handa, Sandeep; Raven, Emma Lloyd (2011-10-12). "The Mechanism of Formation of N -Formylkynurenine by Heme Dioxygenases". Journal of the American Chemical Society. 133 (40): 16251–16257. doi:10.1021/ja207066z. ISSN 0002-7863. PMC 3210546. PMID 21892828.
  13. ^ Booth, Elizabeth S.; Basran, Jaswir; Lee, Michael; Handa, Sandeep; Raven, Emma L. (2015-12-25). "Substrate Oxidation by Indoleamine 2,3-Dioxygenase: EVIDENCE FOR A COMMON REACTION MECHANISM". Journal of Biological Chemistry. 290 (52): 30924–30930. doi:10.1074/jbc.M115.695684. ISSN 0021-9258. PMC 4692220. PMID 26511316.
  14. ^ "Ruskin Junior School - Welcome". www.ruskinjuniorschool.com. Retrieved 2020-08-26.
  15. ^ "Weavers Academy – A Creative Education Trust Academy". www.weaversacademy.org.uk. Retrieved 2020-08-26.
  16. ^ "Grant Mauk | Department of Biochemistry". biochem.ubc.ca. Retrieved 2020-08-26.
  17. ^ "RSC Awards Archive - Inorganic Biochemistry Award". www.rsc.org. Retrieved 2020-08-26.
  18. ^ "RSC Awards Archive - Reaction Kinetics and Mechanisms Award". www.rsc.org. Retrieved 2020-08-26.
  19. ^ "About the Dalton Division". Royal Society of Chemistry. Retrieved 2021-01-04.
  20. ^ "Professor Dan Lloyd". School of Biosciences - University of Kent. Retrieved 2020-08-26.
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