epi-Cedrol synthase (EC 4.2.3.39, 8-epicedrol synthase, epicedrol synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming).[1][2] This enzyme catalyses the following chemical reaction
| epi-cedrol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.39 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate + H2O 8-epi-cedrol + diphosphate
This enzyme is activated by Mg2+.
References
edit- ^ Mercke P, Crock J, Croteau R, Brodelius PE (September 1999). "Cloning, expression, and characterization of epi-cedrol synthase, a sesquiterpene cyclase from Artemisia annua L". Archives of Biochemistry and Biophysics. 369 (2): 213–22. doi:10.1006/abbi.1999.1358. PMID 10486140.
- ^ Hua L, Matsuda SP (September 1999). "The molecular cloning of 8-epicedrol synthase from Artemisia annua". Archives of Biochemistry and Biophysics. 369 (2): 208–12. doi:10.1006/abbi.1999.1357. PMID 10486139.
External links
edit- Epi-cedrol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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