Epsilonpapillomavirus is a genus of viruses in the family Papillomaviridae.[1] Cattle serve as the natural hosts of these bovine papillomaviruses. There are two species in this genus. Diseases associated with this genus include fibropapillomas and true epithelial papillomas of the skin.[2][3]
| Epsilonpapillomavirus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cossaviricota |
| Class: | Papovaviricetes |
| Order: | Zurhausenvirales |
| Family: | Papillomaviridae |
| Genus: | Epsilonpapillomavirus |
Taxonomy
editThe following two species are assigned to the genus:[3]
Structure
editViruses in Epsilonpapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length. The genome codes for 6 proteins.[2]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Epsilonpapillomavirus | Icosahedral | T=7 | Non-enveloped | Circular | Monopartite |
Life cycle
editViral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Bovine serve as the natural host. Transmission routes are contact.[2]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Epsilonpapillomavirus | Bovines | Epithelial: skin | Cell receptor endocytosis | Lysis | Nucleus | Nucleus | Contact |
References
edit- ^ Van Doorslaer, K; Chen, Z; Bernard, HU; Chan, PKS; DeSalle, R; Dillner, J; Forslund, O; Haga, T; McBride, AA; Villa, LL; Burk, RD; ICTV Report Consortium (August 2018). "ICTV Virus Taxonomy Profile: Papillomaviridae". The Journal of General Virology. 99 (8): 989–990. doi:10.1099/jgv.0.001105. PMC 6171710. PMID 29927370.
- ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 10 May 2021.
