Eryx may refer to:
- Eryx (Sicily), an ancient city in Sicily, the modern Erice, Italy
- Mount Eryx, upon which the city stood, the modern Mount Erice
- Eryx (mythology), a mythological king of the Sicilian city of Eryx, and boxer killed by Heracles
- Eryx (missile), an anti-tank missile
- Eryx (snake), a genus of snakes
- "In the Walls of Eryx", a short story by H. P. Lovecraft and K. J. Sterling