Estradiol 3-propionate, or 3-propanoylestradiol, also known as estra-1,3,5(10)-triene-3,17β-diol 3-propionate, is a semisynthetic, steroidal estrogen that was never marketed.[1][2] It is an estrogen ester, specifically, a propionic acid ester of estradiol, and acts as a prodrug to it in vivo.[1][2] The chemical structure of estradiol 3-propionate is contained within estradiol dipropionate, estrapronicate, and orestrate,[3] all of which are also estradiol esters.[2]
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| Other names | Estradiol 3-propanoate; 3-Propanoylestradiol; 3,17β-Hydroxyestra-1,3,5(10)-trien-3-yl propionate |
| Routes of administration | Intramuscular injection, vaginal[1] |
| Drug class | Estrogen; Estrogen ester |
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| Formula | C21H28O3 |
| Molar mass | 328.452 g·mol−1 |
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See also
editReferences
edit- ^ a b c Woolfson AD, Elliott GR, Gilligan CA, Passmore CM (1999). "Design of an intravaginal ring for the controlled delivery of 17 beta-estradiol as its 3-acetate ester". J Control Release. 61 (3): 319–28. doi:10.1016/s0168-3659(99)00148-0. PMID 10477804.
- ^ a b c J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3.
- ^ PubChem. "Estradiol". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-11-02.
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