Exodeoxyribonuclease (phage SP3-induced) (EC 3.1.11.4, phage SP3 DNase, DNA 5′-dinucleotidohydrolase, deoxyribonucleate 5′-dinucleotidase, deoxyribonucleic 5′-dinucleotidohydrolase, bacteriophage SP3 deoxyribonuclease) is an enzyme.[1] that catalyses the following chemical reaction
Exodeoxyribonuclease (phage SP3-induced) | |||||||||
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Identifiers | |||||||||
EC no. | 3.1.11.4 | ||||||||
CAS no. | 37288-30-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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- Exonucleolytic cleavage in the 5′- to 3′-direction to yield nucleoside 5′-phosphates
Preference for single-stranded DNA.
References
edit- ^ Trilling DM, Aposhian HV (May 1968). "Sequential cleavage of dinucleotides from DNA by phage Sp3 DNAse". Proceedings of the National Academy of Sciences of the United States of America. 60 (1): 214–21. Bibcode:1968PNAS...60..214T. doi:10.1073/pnas.60.1.214. PMC 539104. PMID 4968633.
External links
edit- Exodeoxyribonuclease+(phage+SP3-induced) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)