Extracellular matrix protein 2

Extracellular matrix protein 2 is a protein that in humans is encoded by the ECM2 gene.

ECM2
Identifiers
Aliases	ECM2, extracellular matrix protein 2
External IDs	OMIM: 603479; MGI: 3039578; HomoloGene: 1064; GeneCards: ECM2; OMA:ECM2 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) Band 9q22.31 Start 92,493,554 bp End 92,536,655 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 A5 Start 49,658,286 bp End 49,686,265 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon synovial joint right coronary artery parietal pleura skin of hip tibia vena cava germinal epithelium Descending thoracic aorta ascending aorta Top expressed in esophagus aorta muscle of thigh ascending aorta lumbar spinal ganglion lip extraocular muscle aortic valve interventricular septum soleus muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function collagen V binding integrin binding heparin binding collagen binding Cellular component extracellular region interstitial matrix extracellular space extracellular matrix Biological process cell-matrix adhesion extracellular matrix organization axonogenesis positive regulation of cell-substrate adhesion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1842 407800 Ensembl ENSG00000106823 ENSMUSG00000043631 UniProt O94769 Q5FW85 RefSeq (mRNA) NM_001393 NM_001197295 NM_001197296 NM_001012324 RefSeq (protein) NP_001184224 NP_001184225 NP_001384 NP_001012324 Location (UCSC) Chr 9: 92.49 – 92.54 Mb Chr 13: 49.66 – 49.69 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

ECM2 encodes extracellular matrix protein 2, so named because it shares extensive similarity with known extracellular matrix proteins.

Further reading

• Oritani K, Kanakura Y, Aoyama K, et al. (1997). "Matrix glycoprotein SC1/ECM2 augments B lymphopoiesis". Blood. 90 (9): 3404–13. doi:10.1182/blood.V90.9.3404. PMID 9345023.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.