In enzymology, a farnesyl-diphosphate kinase (EC 2.7.4.18) is an enzyme that catalyzes the chemical reaction
| farnesyl diphosphate kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.4.18 | ||||||||
| CAS no. | 50936-43-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- ATP + farnesyl diphosphate ADP + farnesyl triphosphate
Thus, the two substrates of this enzyme are ATP and farnesyl diphosphate, whereas its two products are ADP and farnesyl triphosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:farnesyl-diphosphate phosphotransferase. This enzyme is also called farnesyl pyrophosphate kinase.
References
edit- Shechter I (September 1974). "Phosphate transfer from trans-farnesyl triphosphate to AMP in Gibberella fujikuroi". Biochimica et Biophysica Acta (BBA) - General Subjects. 362 (2): 233–44. doi:10.1016/0304-4165(74)90216-5. PMID 4423368.
