Fenestrel

Fenestrel
Clinical data
Other names	Demethoxycarbestrol; NSC-86465; 2-methyl-3-ethyl-4-phenyl-δ4-cyclohexenecarboxylic acid
ATC code	None;
Identifiers
	IUPAC name 5-Ethyl-6-methyl-4-phenylcyclohex-3-ene-1-carboxylic acid;
CAS Number	7698-97-7;
PubChem CID	24371;
ChemSpider	22786;
UNII	LEC4215V9R;
CompTox Dashboard (EPA)	DTXSID20864106 ;
Chemical and physical data
Formula	C16H20O2
Molar mass	244.334 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1C(C(CC=C1C2=CC=CC=C2)C(=O)O)C;
	InChI InChI=1S/C16H20O2/c1-3-13-11(2)14(16(17)18)9-10-15(13)12-7-5-4-6-8-12/h4-8,10-11,13-14H,3,9H2,1-2H3,(H,17,18); Key:CLMFEXDZPBGYQQ-UHFFFAOYSA-N;

Fenestrel (INN, USAN) (developmental code name ORF-3858) is a synthetic, nonsteroidal estrogen that was developed as a postcoital contraceptive in the 1960s but was never marketed.^[1]^[2]^[3]^[4] Synthesized by Ortho Pharmaceutical in 1961 and studied extensively, it was coined the "morning-after-pill" or "postcoital antifertility agent".^[5] Fenestrel is a seco analogue of doisynolic acid, and a member of the cyclohexenecarboxylic acid series of estrogens.^[6]^[7]

References

^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 517–. ISBN 978-1-4757-2085-3.
^ Milne GW (8 May 2018). Drugs: Synonyms and Properties: Synonyms and Properties. Taylor & Francis. pp. 1407–. ISBN 978-1-351-78989-9.
^ Revaz C, Goldenberg B, Achtari H (January 1971). "[Critical study of new contraceptive methods]". Schweizerische Medizinische Wochenschrift (in French). 101 (3): 92–96. PMID 5544232.
^ Kunjappu MJ (June 2011). "Pioneering studies of the "morning-after" pill". The Yale Journal of Biology and Medicine. 84 (2): 109–111. PMC 3117403. PMID 21698041.
^ Hahn DW, McGuire JL (6 December 2012). "The Use of Pharmacological Agents to Study Implantation". In Glasser SR, Bullock DW (eds.). Cellular and Molecular Aspects of Implantation. Springer Science & Business Media. pp. 478–. ISBN 978-1-4613-3180-3.
^ Kirk RE, Othmer DF (1980). Encyclopedia of chemical technology. Wiley. p. 672. ISBN 978-0-471-02065-3.
^ Acta europaea fertilitatis. Piccin Medical Books. 1969.

This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it.