Festuclavine dehydrogenase (EC 1.5.1.44, FgaFS, festuclavine synthase) is an enzyme with systematic name festuclavine:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction
| Festuclavine dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.5.1.44 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- festuclavine + NAD+ 6,8-dimethyl-6,7-didehydroergoline + NADH + H+
The enzyme takes part in the biosynthesis of fumigaclavine C.
References
edit- ^ Wallwey C, Matuschek M, Xie XL, Li SM (August 2010). "Ergot alkaloid biosynthesis in Aspergillus fumigatus: Conversion of chanoclavine-I aldehyde to festuclavine by the festuclavine synthase FgaFS in the presence of the old yellow enzyme FgaOx3". Organic & Biomolecular Chemistry. 8 (15): 3500–8. doi:10.1039/c003823g. PMID 20526482.
External links
edit- Festuclavine+dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
