Fetal thrombotic vasculopathy

Fetal thrombotic vasculopathy is a chronic disorder characterized by thrombosis in the fetus leading to vascular obliteration and hypoperfusion.

Fetal thrombotic vasculopathy
Intermediate magnification micrograph of the placental disc showing a thrombosed fetal vein, as may be seen in fetal thrombotic vasculopathy. H&E stain.
SpecialtyPathology

It is associated with cerebral palsy and stillbirth.[1]

It is more common in women who have diabetes mellitus.

Diagnosis

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It can be diagnosed by histomorphologic examination of the placenta and is characterized by fetal vessel thrombosis and clustered fibrotic chorionic villi without blood vessels.

See also

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References

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  1. ^ Kraus, FT.; Acheen, VI. (Jul 1999). "Fetal thrombotic vasculopathy in the placenta: cerebral thrombi and infarcts, coagulopathies, and cerebral palsy". Hum Pathol. 30 (7): 759–69. doi:10.1016/s0046-8177(99)90136-3. PMID 10414494.