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Summary
| Description |
English: M–Cdk activity promotes the events of early mitosis, resulting in the metaphase alignment of sister chromatids on the spindle. M–Cdk activity also promotes the activation of APCCdc20, which triggers anaphase and mitotic exit by stimulating the destruction of regulatory proteins, such as securin and cyclins, that govern these events. By promoting cyclin destruction and thus Cdk inactivation, APCCdc20 also triggers activation of APCCdh1, thereby ensuring continued APC activity in G1.[1] |
| Date | |
| Source | The Cell Cycle. Principles of Control. |
| Author | David O Morgan |
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The copyright holder of this file allows anyone to use it for any purpose, provided that the copyright holder is properly attributed. Redistribution, derivative work, commercial use, and all other use is permitted. |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 02:33, 8 April 2020 |  | 750 × 300 (422 KB) | Rob Hurt | Uploaded a work by David O Morgan from The Cell Cycle. Principles of Control. with UploadWizard |
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