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Summary
| Description |
English: 1) The proteasome degrades intracellular proteins into short peptides (2) that are translocated into the endoplasmic reticulum (ER) via the transporter associated with antigen processing (TAP). (3) In the ER, ERAP1 trims these peptides to the proper length (4) to bind Major Histocompatibility Complex (MHC) class I molecules. (5) The MHC class I-peptide complex is transported to the cell surface (6) and presented to immune cells, namely Natural Killer (NK) cells and T cells. Created with BioRender. |
| Date | |
| Source | Own work |
| Author | CAPSTONE-ETN |
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 12:55, 6 May 2024 |  | 1,216 × 1,216 (4.23 MB) | CAPSTONE-ETN | Uploaded while editing "User:CAPSTONE-ETN/sandbox/ERAP1" on en.wikipedia.org |
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