FinP encodes an antisense non-coding RNA gene that is complementary to part of the TraJ 5' UTR. The FinOP system regulates the transfer of F-like plasmids. The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.[1][2]
| FinP | |
|---|---|
 Predicted secondary structure and sequence conservation of FinP | |
| Identifiers | |
| Symbol | FinP |
| Rfam | RF00107 |
| Other data | |
| RNA type | Gene |
| Domain(s) | Bacteria |
| SO | SO:0000644 |
| PDB structures | PDBe |
References
edit- ^ Jerome LJ, van Biesen T, Frost LS (January 1999). "Degradation of FinP antisense RNA from F-like plasmids: the RNA-binding protein, FinO, protects FinP from ribonuclease E". Journal of Molecular Biology. 285 (4): 1457–1473. doi:10.1006/jmbi.1998.2404. PMID 9917389.
- ^ Arthur DC, Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN (December 2003). "FinO is an RNA chaperone that facilitates sense-antisense RNA interactions". The EMBO Journal. 22 (23): 6346–6355. doi:10.1093/emboj/cdg607. PMC 291848. PMID 14633993.
External links
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