Flavonoid 4'-O-methyltransferase (EC 2.1.1.231, SOMT-2, 4'-hydroxyisoflavone methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase.[1] This enzyme catalyses the following chemical reaction
| Flavonoid 4'-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.231 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- S-adenosyl-L-methionine + 4'-hydroxyflavanone S-adenosyl-L-homocysteine + 4'-methoxyflavanone
The enzyme catalyses the 4'-methylation of naringenin.
References
edit- ^ Kim DH, Kim BG, Lee Y, Ryu JY, Lim Y, Hur HG, Ahn JH (September 2005). "Regiospecific methylation of naringenin to ponciretin by soybean O-methyltransferase expressed in Escherichia coli". Journal of Biotechnology. 119 (2): 155–62. doi:10.1016/j.jbiotec.2005.04.004. PMID 15961179.
External links
edit- Flavonoid+4'-O-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
