The flpD RNA motif is a conserved RNA structure discovered using bioinformatics.[1] It is detected only in methanogenic archaea, and is generally located in the apparent 5' untranslated region of genes encoding hydrogenases that are likely involved in methane metabolism. For example, the flpD gene itself encodes a subunit of methyl-viologen-reducing hydrogenase.[2]
| flpD RNS motif | |
|---|---|
 Consensus secondary structure of flpD RNAs | |
| Identifiers | |
| Symbol | flpD RNA |
| Rfam | RF01737 |
| Other data | |
| RNA type | Cis-regulatory element |
| Domain(s) | Archaea |
| PDB structures | PDBe |
References
edit- ^ Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605.
- ^ Nölling J, Pihl TD, Vriesema A, Reeve JN (May 1995). "Organization and growth phase-dependent transcription of methane genes in two regions of the Methanobacterium thermoautotrophicum genome". J. Bacteriol. 177 (9): 2460–2468. doi:10.1128/jb.177.9.2460-2468.1995. PMC 176905. PMID 7730278.
External links
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