The folP RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] folP motifs are found in the genus Dialister.
| folP | |
|---|---|
 Consensus secondary structure and sequence conservation of folP RNA | |
| Identifiers | |
| Symbol | folP |
| Rfam | RF02978 |
| Other data | |
| RNA type | Cis-reg |
| SO | SO:0005836 |
| PDB structures | PDBe |
folP motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. The RNAs are, in most cases, followed by Rho-independent transcription terminators, which might participate in the cis regulation performed by folP RNAs. The RNAs are upstream of genes encoding dihydropteroate synthase, which is involved in folate metabolism.
References
edit- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.