Fowles is the surname of the following people:
- Colin Fowles (1953−1985), Jamaican-American soccer player
- Glenys Fowles (born 1941 or 1946), Australian operatic soprano
- Ian Fowles (born 1979), American guitarist
- John Fowles (1926-2005), English writer
- Sylvia Fowles (born 1985), American basketball player