Francis Hamilton may refer to:
- Sir Francis Hamilton, 1st Baronet, of Killock, Irish landowner and politician
- Francis Buchanan-Hamilton (1762–1829), later known as Francis Hamilton, Scottish physician and naturalist
- Francis Alvin George Hamilton, Canadian politician usually known as Alvin Hamilton
- Sir Francis Hamilton, 3rd Baronet (c. 1637–1714)
See also
edit- Frank Hamilton (disambiguation)
- Francis Hamilton Wedgwood of Wedgwood Pottery