Frederick Guthrie may refer to:
- Frederick Guthrie (scientist) (1833–1886), British physicist, chemist, and academic
- Frederick Guthrie (bass) (1924–2008), American operatic bass
- Frederick Bickell Guthrie (1861–1927), Australian agricultural chemist and a president of the Royal Society of New South Wales.
- Frederick Guthrie Tait (1861–1927), Scottish golfer and soldier
This disambiguation page lists articles about people with the same name.
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