Frederick Muhlenberg (1750–1801) was the first Speaker of the U.S. House of Representatives.
Frederick Muhlenberg may also refer to:
- Frederick Augustus Muhlenberg (1887–1980), architect, Army officer and U.S. congressman from Pennsylvania
- Frederick Augustus Muhlenberg (educator) (1818–1901), president of Muhlenberg College
See also
edit- Portrait of Frederick Muhlenberg, portrait of Frederick Muhlenberg (1750–1801) by Joseph Wright