Fructose 5-dehydrogenase

In enzymology, a fructose 5-dehydrogenase (EC 1.1.99.11) is an enzyme that catalyzes the chemical reaction

fructose 5-dehydrogenase
Identifiers
EC no.1.1.99.11
CAS no.37250-85-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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D-fructose + acceptor 5-dehydro-D-fructose + reduced acceptor

Thus, the two substrates of this enzyme are D-fructose and acceptor, whereas its two products are 5-dehydro-D-fructose and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-fructose:acceptor 5-oxidoreductase. Other names in common use include fructose 5-dehydrogenase (acceptor), D-fructose dehydrogenase, and D-fructose:(acceptor) 5-oxidoreductase.

References

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  • Ameyama M; Adachi O (1982). "D-Fructose dehydrogenase from Gluconobacter industrius, membrane-bound". Carbohydrate Metabolism - Part D. Methods in Enzymology. Vol. 89. pp. 154–159. doi:10.1016/S0076-6879(82)89027-7. ISBN 978-0-12-181989-7.
  • Yamada Y, Aida K, Uemura T (May 1967). "Enzymatic studies on the oxidation of sugar and sugar alcohol. I Purification and properties of particle-bound fructose dehydrogenase". J. Biochem. 61 (5). Tokyo: 636–46. doi:10.1093/oxfordjournals.jbchem.a128594. PMID 6059959.