GBP5

Guanylate binding protein 5 is a protein in humans that is encoded by the GBP5 gene.

GBP5
Identifiers
Aliases	GBP5, GBP-5, guanylate binding protein 5
External IDs	OMIM: 611467; MGI: 2429943; HomoloGene: 14183; GeneCards: GBP5; OMA:GBP5 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1p22.2 Start 89,256,189 bp End 89,272,860 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3|3 H1 Start 142,199,739 bp End 142,228,105 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte appendix monocyte blood lymph node spleen bone marrow cells gallbladder right uterine tube testicle Top expressed in spleen urinary bladder thymus white adipose tissue jejunum ileum quadriceps femoris muscle bone marrow islet of Langerhans muscle tissue More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding GTP binding protein binding hydrolase activity GTPase activity identical protein binding protein homodimerization activity Cellular component cytoplasm Golgi membrane Golgi apparatus membrane cytoplasmic vesicle perinuclear region of cytoplasm Biological process immune system process positive regulation of cytokine production involved in inflammatory response inflammatory response positive regulation of NLRP3 inflammasome complex assembly protein homotetramerization positive regulation of innate immune response cellular response to interferon-gamma response to bacterium protein localization to Golgi apparatus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 115362 229898 Ensembl ENSG00000154451 ENSMUSG00000105504 UniProt Q96PP8 Q8CFB4 RefSeq (mRNA) NM_052942 NM_001134486 NM_001391920 NM_153564 NM_212440 RefSeq (protein) NP_001127958 NP_443174 NP_705792 Location (UCSC) Chr 1: 89.26 – 89.27 Mb Chr 3: 142.2 – 142.23 Mb PubMed search
Wikidata
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See also

• Guanylate, conjugate base of guanosine monophosphate
• Guanylate-binding protein