Gammapapillomavirus is a genus of viruses in the family Papillomaviridae.[1] Human serve as their natural hosts. There are 27 species in this genus. Diseases associated with this genus include warts and papillomas.[2][3]
| Gammapapillomavirus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Monodnaviria |
| Kingdom: | Shotokuvirae |
| Phylum: | Cossaviricota |
| Class: | Papovaviricetes |
| Order: | Zurhausenvirales |
| Family: | Papillomaviridae |
| Genus: | Gammapapillomavirus |
Taxonomy
editThe following 27 species are assigned to the genus:[3]
- Gammapapillomavirus 1
- Gammapapillomavirus 2
- Gammapapillomavirus 3
- Gammapapillomavirus 4
- Gammapapillomavirus 5
- Gammapapillomavirus 6
- Gammapapillomavirus 7
- Gammapapillomavirus 8
- Gammapapillomavirus 9
- Gammapapillomavirus 10
- Gammapapillomavirus 11
- Gammapapillomavirus 12
- Gammapapillomavirus 13
- Gammapapillomavirus 14
- Gammapapillomavirus 15
- Gammapapillomavirus 16
- Gammapapillomavirus 17
- Gammapapillomavirus 18
- Gammapapillomavirus 19
- Gammapapillomavirus 20
- Gammapapillomavirus 21
- Gammapapillomavirus 22
- Gammapapillomavirus 23
- Gammapapillomavirus 24
- Gammapapillomavirus 25
- Gammapapillomavirus 26
- Gammapapillomavirus 27
Structure
editViruses in Gammapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length.[2]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Gammapapillomavirus | Icosahedral | T=7 | Non-enveloped | Circular | Monopartite |
Life cycle
editViral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Human serve as the natural host. Transmission routes are contact.[2]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Gammapapillomavirus | Humans | Epithelial: mucous; epithelial: skin | Cell receptor endocytosis | Lysis | Nucleus | Nucleus | Contact |
References
edit- ^ Van Doorslaer, K; Chen, Z; Bernard, HU; Chan, PKS; DeSalle, R; Dillner, J; Forslund, O; Haga, T; McBride, AA; Villa, LL; Burk, RD; ICTV Report Consortium (August 2018). "ICTV Virus Taxonomy Profile: Papillomaviridae". The Journal of General Virology. 99 (8): 989–990. doi:10.1099/jgv.0.001105. PMC 6171710. PMID 29927370.
- ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 10 May 2021.