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Most vaccines consist of viruses that have been attenuated, disabled, weakened or killed in some way so that their virulent properties are no longer effective. A simple genetically modified vaccine, based on a thymidine kinase deficient mutant of pseudorabies virus was reportedly available as early as 2001 as a commercial vaccine to control Aujeszky's disease in Europe, North America and Japan.[1]
References
edit- ^ Stephenson, John (2001). "Genetically Modified Viruses Vaccines by Design". Current Pharmaceutical Biotechnology. 2 (1): 47–76. doi:10.2174/1389201013378815. PMID 11482348.
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