George and Dragon may refer to:
- George and Dragon, Great Budworth, a Grade II listed building in Cheshire, England
- The George Inn, Southwark, a public house in Southwark, London, established as George and Dragon in the medieval period
- George and Dragon, Fitzrovia, a public house in the Fitzrovia district of London
- George and Dragon, Salisbury, in Wiltshire, England
- A comic strip in The Dandy