Geranylgeraniol 18-hydroxylase (EC 1.14.13.110, GGOH-18-hydroxylase) is an enzyme with systematic name geranylgeraniol,NADPH:oxygen oxidoreductase (18-hydroxylating).[1] This enzyme catalyses the following chemical reaction
| Geranylgeraniol 18-hydroxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.110 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- geranylgeraniol + NADPH + H+ + O2 18-hydroxygeranylgeraniol + NADP+ + H2O
Geranylgeraniol 18-hydroxylase is a heme-thiolate protein (P-450).
References
edit- ^ Tansakul P, De-Eknamkul W (1998). "Geranylgeraniol-18-hydroxylase: the last enzyme in the plaunotol biosynthetic pathway in Croton sublyratus". Phytochemistry. 47 (7): 1241–1246. doi:10.1016/s0031-9422(97)00743-7.
External links
edit- Geranylgeraniol+18-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
