Glucosamine N-acetyltransferase

In enzymology, a glucosamine N-acetyltransferase (EC 2.3.1.3) is an enzyme that catalyzes the chemical reaction

glucosamine N-acetyltransferase
Glucosamine N-acetyltransferase homodimer, Rhizomucor miehei
Identifiers
EC no.2.3.1.3
CAS no.9032-94-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins
acetyl-CoA + D-glucosamine CoA + N-acetyl-D-glucosamine

Thus, the two substrates of this enzyme are acetyl-CoA and D-glucosamine, whereas its two products are CoA and N-acetyl-D-glucosamine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:D-glucosamine N-acetyltransferase. Other names in common use include glucosamine acetylase, and glucosamine acetyltransferase. This enzyme participates in aminosugars metabolism.

References

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  • CHOU TC, SOODAK M (1952). "The acetylation of d-glucosamine by pigeon liver extracts". J. Biol. Chem. 196 (1): 105–9. PMID 12980946.