In enzymology, a glucosamine N-acetyltransferase (EC 2.3.1.3) is an enzyme that catalyzes the chemical reaction
| glucosamine N-acetyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Glucosamine N-acetyltransferase homodimer, Rhizomucor miehei | |||||||||
| Identifiers | |||||||||
| EC no. | 2.3.1.3 | ||||||||
| CAS no. | 9032-94-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- acetyl-CoA + D-glucosamine CoA + N-acetyl-D-glucosamine
Thus, the two substrates of this enzyme are acetyl-CoA and D-glucosamine, whereas its two products are CoA and N-acetyl-D-glucosamine.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:D-glucosamine N-acetyltransferase. Other names in common use include glucosamine acetylase, and glucosamine acetyltransferase. This enzyme participates in aminosugars metabolism.
References
edit- CHOU TC, SOODAK M (1952). "The acetylation of d-glucosamine by pigeon liver extracts". J. Biol. Chem. 196 (1): 105–9. PMID 12980946.
