Glycerol-3-phosphate 2-O-acyltransferase

Glycerol-3-phosphate 2-O-acyltransferase (EC 2.3.1.198, sn-2-glycerol-3-phosphate O-acyltransferase, glycerol-3-phosphate O-acyltransferase) is an enzyme with systematic name acyl-CoA:sn-glycerol 3-phosphate 2-O-acyltransferase.[1] This enzyme catalyses the following chemical reaction

Glycerol-3-phosphate 2-O-acyltransferase
Identifiers
EC no.2.3.1.198
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
acyl-CoA + sn-glycerol 3-phosphate CoA + a 2-acyl-sn-glycerol 3-phosphate

This membrane-associated enzyme is required for suberin or cutin synthesis in plants.

References

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  1. ^ Yang W, Pollard M, Li-Beisson Y, Beisson F, Feig M, Ohlrogge J (June 2010). "A distinct type of glycerol-3-phosphate acyltransferase with sn-2 preference and phosphatase activity producing 2-monoacylglycerol". Proceedings of the National Academy of Sciences of the United States of America. 107 (26): 12040–5. Bibcode:2010PNAS..10712040Y. doi:10.1073/pnas.0914149107. PMC 2900678. PMID 20551224.
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