In enzymology, a glycoprotein N-palmitoyltransferase (EC 2.3.1.96) is an enzyme that catalyzes the chemical reaction
glycoprotein N-palmitoyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.3.1.96 | ||||||||
CAS no. | 97162-74-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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- palmitoyl-CoA + glycoprotein CoA + N-palmitoylglycoprotein
Thus, the two substrates of this enzyme are palmitoyl-CoA and glycoprotein, whereas its two products are CoA and N-palmitoylglycoprotein.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl-CoA:glycoprotein N-palmitoyltransferase. This enzyme is also called mucus glycoprotein fatty acyltransferase. This enzyme participates in aminosugars metabolism. This enzyme has at least one effector, Dithiothreitol.
References
edit- Liau YH, Slomiany BL, Slomiany A, Piasek A, Palmer D, Rosenthal WS (1985). "Identification of mucus glycoprotein fatty acyltransferase activity in human gastric mucosa". Digestion. 32 (1): 57–62. doi:10.1159/000199218. PMID 4018446.