In enzymology, a glycoprotein O-fatty-acyltransferase (EC 2.3.1.142) is an enzyme that catalyzes the chemical reaction
| glycoprotein O-fatty-acyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.142 | ||||||||
| CAS no. | 122191-29-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- palmitoyl-CoA + mucus glycoprotein CoA + O-palmitoylglycoprotein
Thus, the two substrates of this enzyme are palmitoyl-CoA and mucus glycoprotein, whereas its two products are CoA and O-palmitoylglycoprotein.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase. This enzyme is also called protein acyltransferase.
References
edit- Kasinathan C, Grzelinska E, Okazaki K, Slomiany BL, Slomiany A (1990). "Purification of protein fatty acyltransferase and determination of its distribution and topology". J. Biol. Chem. 265 (9): 5139–44. PMID 2318887.
