Graham Simpson may refer to:
- Graham Simpson (businessman) (born 1946), former chairman of Watford F.C and owner of Simpson Travel
- Graham Simpson (doctor), practitioner of proactive medicine and founding member of American Holistic Medical Association
- Graham Simpson (musician) (1943–2012), founding member and bassist of Roxy Music
- Graham Simpson (politician), Scottish politician and Member of the Scottish Parliament for Central Scotland
- Graham Simpson (badminton), see Scotland at the 2002 Commonwealth Games