Grenier is a surname. It is a French word for attic, loft, or granary. Notable people with the surname include:
- Adrian Grenier
- Angèle Grenier, Canadian maple syrup producer
- Auguste Jean François Grenier (1814–1890), French doctor and entomologist
- Clément Grenier
- Eustace Grenier
- Hugo Grenier, French tennis player
- Jacques de Grenier (1736–1803), French Navy officer
- Jean Charles Marie Grenier (1808–1875), French botanist and naturalist
- John Grenier
- Louis Grenier, fictional character
- Martin Grenier
- Paul Grenier (1768–1827), French general
- Philippe Grenier
- Richard Grenier (disambiguation)
- Robert Grenier (CIA officer)
- Robert Grenier (poet)
- Roger Grenier
- Suzanne Blais-Grenier
- Sylvain Grenier
- Walter I Grenier, Lord of Caesarea
- Zach Grenier