Guanylate binding protein family member 6

Guanylate binding protein family member 6 is a protein that in humans is encoded by the GBP6 gene. [5]

GBP6
Identifiers
AliasesGBP6, guanylate binding protein family member 6
External IDsOMIM: 612467; MGI: 97072; HomoloGene: 128731; GeneCards: GBP6; OMA:GBP6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_198460
NM_001320257

RefSeq (protein)

NP_001307186
NP_940862

n/a

Location (UCSC)Chr 1: 89.36 – 89.39 MbChr 5: 105.26 – 105.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000183347Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000079363Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Guanylate binding protein family member 6". Retrieved 2017-07-27.

Further reading

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  • Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M (2010). "New genetic associations detected in a host response study to hepatitis B vaccine". Genes Immun. 11 (3): 232–8. doi:10.1038/gene.2010.1. PMID 20237496.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.