Gwen may refer to:
- Gwen (given name), including a list of people with the name
- Gwen (singer), a member of the Filipino Pinoy pop group Bini
- Gwen, or the Book of Sand, a 1985 animated film
- Gwen (film), a 2018 horror film
- Tropical Storm Gwen, several storms with the name
Acronyms
edit- AN/URC-117 Ground Wave Emergency Network, a military command and control communications system
- Guild Wars: Eye of the North (GW:EN), an expansion pack for a massively multiplayer online role-playing game