HDGFRP3

Hepatoma-derived growth factor, related protein 3, also known as HDGFRP3, is a human gene.

HDGFL3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1N27
Identifiers
Aliases	HDGFL3, CGI-142, HDGF-2, HDGF2, HRP-3, HDGFRP3, hepatoma-derived growth factor, related protein 3, HDGF like 3
External IDs	OMIM: 616643; MGI: 1352760; HomoloGene: 32196; GeneCards: HDGFL3; OMA:HDGFL3 - orthologs
Gene location (Human) Chr. Chromosome 15 (human) Band 15q25.2 Start 83,112,738 bp End 83,207,823 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 D3 Start 81,530,999 bp End 81,584,221 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence Achilles tendon ventricular zone Brodmann area 23 entorhinal cortex postcentral gyrus orbitofrontal cortex corpus epididymis Region I of hippocampus proper endothelial cell Top expressed in Rostral migratory stream barrel cortex ganglionic eminence medial ganglionic eminence mandibular prominence maxillary prominence ventromedial nucleus lateral septal nucleus human fetus paraventricular nucleus of hypothalamus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function microtubule binding tubulin binding growth factor activity Cellular component cytoplasm cytosol nucleus nucleoplasm extracellular region Biological process negative regulation of microtubule depolymerization microtubule polymerization cell population proliferation neuron projection development regulation of signaling receptor activity signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 50810 29877 Ensembl ENSG00000166503 ENSMUSG00000025104 UniProt Q9Y3E1 Q9JMG7 RefSeq (mRNA) NM_016073 NM_013886 RefSeq (protein) NP_057157 NP_038914 Location (UCSC) Chr 15: 83.11 – 83.21 Mb Chr 7: 81.53 – 81.58 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Vandegraaff N, Devroe E, Turlure F, et al. (2006). "Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication". Virology. 346 (2): 415–26. doi:10.1016/j.virol.2005.11.022. PMID 16337983.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Cherepanov P, Devroe E, Silver PA, Engelman A (2005). "Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase". J. Biol. Chem. 279 (47): 48883–92. doi:10.1074/jbc.M406307200. PMID 15371438.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
• Ikegame K, Yamamoto M, Kishima Y, et al. (2000). "A new member of a hepatoma-derived growth factor gene family can translocate to the nucleus". Biochem. Biophys. Res. Commun. 266 (1): 81–7. doi:10.1006/bbrc.1999.1733. PMID 10581169.