HLA-B*82





major histocompatibility complex (human), class I, B82
Alleles	B*8201
Structure (See HLA-B)
Symbol(s)	HLA-B
Locus	chr.6 6p21.31

HLA-B*82 (B*82) is an HLA-B allele-group. There is no current useful serotyping for HLA-B*82 gene products.^[1] B*8201 was first identified by sequence analysis and appears to be derived by gene conversion between B*5602 and another HLA class I allele.,^[2] later B*8202 was identified in a caucasian and was suggested to be ancestral to B*8201, as product between gene conversion of B*5602 allele and B*4501 allele. B*82 is more common in East Africa, Kenya and Sudan, the frequency of B*8201 is found in the peoples to the west, sporadically in Central and West Africa, and B*8202 is found in Sudan and Saudi Arabia.^[3]

Serotype

B82 serotype recognition of Some HLA B*82 allele-group gene products^[4]
B*82	B82	other	Sample
allele	%	%	size (N)
*8201	3	79	146

Allele frequencies

**HLA B*8201 frequencies**
		freq
ref.	Population	(%)
^[5]	Luo (Kenya)	1.9
^[5]	Guinea Bissau	0.8
^[5]	Natal Zulu (S. Africa)	0.5
^[5]	Beti (Cameroon)	0.3
^[5]	Kenya	0.3
^[5]	Kampala (Uganda)	0.3
^[5]	Nandi (Kenya)	0.2
'
HLA B8202 frequencies**
^[5]	Sudanese	2.5
^[5]	Kenya	0.7
^[5]	Guraiat and Hail (Saudi Arabia)	0.2

References

^ Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
^ Hurley CK, Steiner N, Hoyer RJ, et al. (1996). "Novel HLA-B alleles, B*8201, B*3515 and B*5106, add to the complexity of serologic identification of HLA types". Tissue Antigens. 47 (3): 179–87. doi:10.1111/j.1399-0039.1996.tb02538.x. PMID 8740766.
^ Cox ST, Hossain E, McWhinnie A, Prokupek B, Madrigal JA, Little AM (2000). "HLA-B*8202 identified in a Caucasoid potential bone marrow donor". Tissue Antigens. 56 (2): 188–91. doi:10.1034/j.1399-0039.2000.560216.x. PMID 11019925.
^ derived from IMGT/HLA
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.

[pmid15787720-1] Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.

[pmid8740766-2] Hurley CK, Steiner N, Hoyer RJ, et al. (1996). "Novel HLA-B alleles, B*8201, B*3515 and B*5106, add to the complexity of serologic identification of HLA types". Tissue Antigens. 47 (3): 179–87. doi:10.1111/j.1399-0039.1996.tb02538.x. PMID 8740766.

[pmid11019925-3] Cox ST, Hossain E, McWhinnie A, Prokupek B, Madrigal JA, Little AM (2000). "HLA-B*8202 identified in a Caucasoid potential bone marrow donor". Tissue Antigens. 56 (2): 188–91. doi:10.1034/j.1399-0039.2000.560216.x. PMID 11019925.

[4] rived from IMGT/HLA

[pmid12753660-5] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.

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