HLA-B associated transcript 3

Large proline-rich protein BAT3 is a protein that in humans is encoded by the BAT3 gene.[5][6]

BAG6
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesBAG6, BAG-6, BAT3, D6S52E, G3, HLA-B associated transcript 3, BCL2 associated athanogene 6, BAG cochaperone 6
External IDsOMIM: 142590; MGI: 1919439; HomoloGene: 3409; GeneCards: BAG6; OMA:BAG6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001252468
NM_001252469
NM_057171

RefSeq (protein)

NP_001092004
NP_001186626
NP_001186627
NP_542433
NP_542434

Location (UCSC)Chr 6: 31.64 – 31.65 MbChr 17: 35.14 – 35.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is a nuclear protein. It has been implicated in the control of apoptosis and regulating heat shock protein. There are three alternatively spliced transcript variants described for this gene.[6]

References

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  1. ^ a b c ENSG00000228760, ENSG00000234651, ENSG00000229524, ENSG00000096155, ENSG00000227761, ENSG00000233348 GRCh38: Ensembl release 89: ENSG00000204463, ENSG00000228760, ENSG00000234651, ENSG00000229524, ENSG00000096155, ENSG00000227761, ENSG00000233348Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024392Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Banerji J, Sands J, Strominger JL, Spies T (Apr 1990). "A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain". Proc Natl Acad Sci U S A. 87 (6): 2374–8. Bibcode:1990PNAS...87.2374B. doi:10.1073/pnas.87.6.2374. PMC 53689. PMID 2156268.
  6. ^ a b "Entrez Gene: BAT3 HLA-B associated transcript 3".

Further reading

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