Two vessels of the British Royal Navy have been named HMS Sesame:
- HMS Sesame (1918) was an S-class destroyer launched in 1918 and scrapped in 1934–1936
- HMS Sesame (W144) was an Assurance-class rescue tug torpedoed and sunk by a German E-boat off Normandy, France in June 1944
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.