Hayrapetyan (Armenian: Հայրապետյան) or in Western Armenian Հայրապետեան pronounced Hairabedian is an Armenian surname. It is also transliterated as Hayrapetian, Hairapetyan, Hayrapetyan, Hairapetian, Ayrapetyan, Airapetyan or Airapetian and may refer to:
- Aram Ayrapetyan (born 1986), Russian-Armenian football player
- Arsen Ayrapetyan (born 1997), Russian football player
- Arshak Hayrapetyan (born 1978), Armenian sport wrestler
- David Ayrapetyan (born 1983), Russian-Armenian amateur boxer
- Eduard Hayrapetyan (born 1949), Armenian composer
- Levon Hayrapetyan (born 1989), Armenian footballer
- Luara Hayrapetyan (born 1997), Armenian singer
- Melanie Gabriella Hayrapetian, known as Melanie Wehbe (born 1991), Swedish singer
- Sarkis Hayrapetyan (born 1992), Armenian figure skater
- Slavik Hayrapetyan (born 1996), Armenian figure skater
- Sos Hayrapetyan (born 1959), Armenian Soviet field hockey player
- Stefan Airapetjan (born 1997), Estonian singer