Hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase

Hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase (EC 3.2.1.168) is an enzyme with systematic name hesperetin 7-(6-O-alpha-L-rhamnopyranosyl-beta-D-glucopyranoside) 6-O-alpha-rhamnopyranosyl-beta-glucohydrolase.[1][2] This enzyme catalyses the following chemical reaction

Hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase
Identifiers
EC no.3.2.1.168
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins
hesperidin + H2O ⇌ hesperetin + rutinose

The enzyme exhibits high specificity towards 7-O-linked flavonoid beta-rutinosides.

The enzyme is produced by the fungus Acremonium sp. DSM24697. The genera Acremonium and morphologically similar Stilbella have not yet been fully studied on a molecular basis. Under the morphological basis, the fungus Stilbella fimetaria SES201 was reidentified as Acremonium sp. SES201 = DSM24697.

References

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  1. ^ Mazzaferro L, Piñuel L, Minig M, Breccia JD (May 2010). "Extracellular monoenzyme deglycosylation system of 7-O-linked flavonoid β-rutinosides and its disaccharide transglycosylation activity from Stilbella fimetaria". Archives of Microbiology. 192 (5): 383–93. doi:10.1007/s00203-010-0567-7. hdl:11336/81705. PMID 20358178.
  2. ^ Mazzaferro L, Piñuel L, Minig M, Breccia JD (2011). "Erratum to: Extracellular monoenzyme deglycosylation system of 7-O-linked flavonoid β-rutinosides and its disaccharide transglycosylation activity from Stilbella fimetaria". Archives of Microbiology. 193 (6): 461. doi:10.1007/s00203-011-0709-6.
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