In enzymology, a hexadecanal dehydrogenase (acylating) (EC 1.2.1.42) is an enzyme that catalyzes the chemical reaction
| hexadecanal dehydrogenase (acylating) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.2.1.42 | ||||||||
| CAS no. | 72561-01-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- hexadecanal + CoA + NAD+ hexadecanoyl-CoA + NADH + H+
The 3 substrates of this enzyme are hexadecanal, CoA, and NAD+, whereas its 3 products are hexadecanoyl-CoA, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hexadecanal:NAD+ oxidoreductase (CoA-acylating). This enzyme is also called fatty acyl-CoA reductase.
References
edit- Johnson RC, Gilbertson JR (1972). "Isolation, characterization, and partial purification of a fatty acyl coenzyme A reductase from bovine cardiac muscle". J. Biol. Chem. 247 (21): 6991–8. PMID 4343165.
