Heyes is a surname. Notable people with the surname include:
- Cecilia Heyes, academic
- Cressida Heyes (born 1970), Canadian philosopher
- Darren Heyes (born 1978), English footballer
- David Heyes (born 1946), English politician
- David Heyes (cricketer) (born 1967), English cricketer
- Douglas Heyes (1919–1993), American screenwriter and film producer
- Harry Heyes (1895–?), English footballer
- Herbert Heyes (1889–1958), American actor
- Mark Heyes, Scottish television presenter
- Tasman Heyes (1896–1980), Australian civil servant
- Thomas Heyes, English publisher