Hopoate is a Tongan surname. Notable people with this surname include:
- John Hopoate (born 1974), Australian rugby league player
- Albert Hopoate (rugby league, born 1985), Australian rugby league player, younger brother of John
- William Hopoate (born 1992) Australian rugby league player, son of John
- Jamil Hopoate (born 1994) Australian rugby league player and convicted criminal, son of John
- Albert Hopoate (rugby league, born 2001), Australian rugby league player, son of John